Extracellular Vesicles Including Exosomes for Hair Follicle Regeneration

    January 2022 in “ Stem cell biology and regenerative medicine ”
    Edith Aberdam, Alizée le Riche, Sylvie Bordes, B. Closs, Byung-Soon Park, Daniel Aberdam
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    TLDR Extracellular vesicles, including exosomes from certain cells, can stimulate hair growth.
    The document discusses the role of extracellular vesicles, including exosomes, in hair follicle regeneration. Studies have shown that these vesicles, derived from cell types like mesenchymal stem cells (MSCs) and macrophages, can stimulate hair growth. For example, a study showed that extracellular vesicles from MSCs activated dermal papilla cells and promoted the conversion of hair follicles from the resting phase to the growth phase in mice. Another study demonstrated that macrophage-derived extracellular vesicles also promote hair growth. The document also suggests that growth factors and signaling pathways may play a role in this process.
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