Botulinum Toxin in the Treatment of Hair and Scalp Disorders: Current Evidence and Clinical Applications

    March 2025 in “ Toxins
    Sofia M. Perez, Sarah A. AlSalman, Betty Nguyen, Antonellá Tosti
    TLDR Botulinum toxin shows promise for treating scalp sweating but not for hair growth.
    This systematic review evaluates the use of Botulinum toxin (BoNT) in treating hair and scalp disorders, analyzing 40 studies with 689 patients. It finds that BoNT-A minimally promotes hair growth in androgenetic alopecia (AGA) patients, but results are not statistically significant, making it difficult to recommend over established AGA treatments. BoNT-A and B show significant efficacy in treating craniofacial hyperhidrosis with minimal side effects. The review highlights the need for larger, controlled studies to better understand BoNT's clinical value in various scalp conditions, as current evidence is limited.
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