TLDR Botulinum toxin might help with some scalp conditions, but more research is needed to confirm its effectiveness and safety.
The systematic review "Botulinum Toxin for Scalp Conditions" analyzed 24 original articles, including 12 case reports, 9 clinical trials, and 3 case series, involving 309 patients with scalp conditions treated with botulinum toxin (BTX). The conditions with the most substantial data supporting the clinical efficacy of BTX were androgenetic alopecia, craniofacial hyperhidrosis, and scalp hyperseborrhea. However, the quality of evidence is highly variable and, for many conditions, limited to small observational studies. The review concludes that BTX may be a promising therapeutic option for various scalp conditions, but future studies are needed to better understand its efficacy and safety.
Cited in this study
8 / 8 results
2 citations
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August 2022 in “Dermatologic Therapy” Both botulinum toxin A and multivitamin mesotherapy effectively treat hair loss, with botulinum toxin A being the better single-session option.
June 2022 in “Journal of Cosmetic Dermatology” 
3 citations
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January 2022 in “Journal of Cosmetic Dermatology” Botox can effectively treat hair loss with some side effects and high cost, while LC hair serum also shows great results with fewer side effects.
15 citations
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April 2020 in “Journal of The American Academy of Dermatology” Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
11 citations
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January 2019 in “Skin appendage disorders” Hyaluronic acid injections can cause hair loss due to blocked blood vessels.
24 citations
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July 2017 in “Journal of Cutaneous and Aesthetic Surgery” Botulinum toxin was found to be a safe and effective treatment for male pattern baldness in a small test, but more research is needed.
24 citations
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December 2010 in “Dermatologic surgery” Botulinum toxin type A injections are not effective for severe alopecia areata.
50 citations
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November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
