Assessing the Efficacy and Quality of Life Improvements of Botulinum Toxin Type A with Topical Minoxidil Versus Topical Minoxidil in Male Androgenetic Alopecia: A Randomized Controlled Trial

    Linli Yu, Sathishkumar Moorthy, Xutong Li … Xin Huang
    Studysummary This study found that in male patients with androgenetic alopecia, combining botulinum toxin type A with 5% Minoxidil significantly improved hair growth, patient satisfaction, and quality of life over six months, compared to using Minoxidil alone, without causing adverse effects.
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    Research cited in this study 21

    1. Prospective Efficacy and Safety Study of an Innovative Kerascalp Hair Growth Serum in Mild-to-Moderate Alopecia in India: Regrowth Study Cureus · 2023
    2. Evaluation of Anxiety and Depression in Patients with Androgenetic Alopecia in Shanghai: A Cross-Sectional Study Dermatologic Therapy · 2023
    3. Quality of Life and Its Association With Androgenetic Alopecia Patients in Shanghai: A Cross-Sectional Study Clinical, Cosmetic and Investigational Dermatology · 2022
    4. A Study of Combination Unilateral Subcutaneous Botulinum Toxin A Treatment for Androgenetic Alopecia Journal of Cosmetic Dermatology · 2022
    5. Efficacy of Botulinum Toxin A Injection in the Treatment of Androgenic Alopecia: A Comparative Controlled Study Journal of Cosmetic Dermatology · 2022
    6. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    7. Use of Botulinum Toxin for Androgenic Alopecia: A Systematic Review Skin appendage disorders · 2021
    8. Is There a Rationale for the Use of Botulinum Toxin in the Treatment of Androgenetic Alopecia? Journal of Cosmetic Dermatology · 2021
    9. Androgenetic Alopecia: Update on Etiology Dermatological reviews · 2021
    10. Therapeutic Use of Botulinum Neurotoxins in Dermatology: Systematic Review Toxins · 2021
    11. Trichoscopic Findings in Androgenetic Alopecia Medicinski arhiv · 2021
    12. A Randomized, Single-Blinded, Vehicle-Controlled Study of a Topical Active Blend in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2020
    13. Randomized Trial of Electrodynamic Microneedling Combined with 5% Minoxidil Topical Solution for Treating Androgenetic Alopecia in Chinese Males and Molecular Mechanistic Study of the Involvement of the Wnt/β-Catenin Signaling Pathway Journal of Dermatological Treatment · 2020
    14. The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism Journal of The American Academy of Dermatology · 2020
    15. A Review of the Treatment of Male Pattern Hair Loss Expert Opinion on Pharmacotherapy · 2020
    16. Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia BioMed Research International · 2020
    17. The Effect of 1540-nm Fractional Erbium-Glass Laser in the Treatment of Androgenic Alopecia Journal of Cosmetic Dermatology · 2019
    18. A Randomized, Investigator-Blinded, Controlled, Split-Scalp Study of the Efficacy and Safety of a 1550-nm Fractional Erbium-Glass Laser, Used in Combination with Topical 5% Minoxidil Versus 5% Minoxidil Alone, for the Treatment of Androgenetic Alopecia Lasers in Medical Science · 2019
    19. A Small Dose of Botulinum Toxin A Is Effective for Treating Androgenetic Alopecia in Chinese Patients Dermatologic Therapy · 2018
    20. Androgenetic Alopecia: Drug Safety and Therapeutic Strategies Expert Opinion on Drug Safety · 2018
    21. A Hypothetical Pathogenesis Model for Androgenic Alopecia: Clarifying the Dihydrotestosterone Paradox and Rate-Limiting Recovery Factors Medical Hypotheses · 2017

    Related research 2

    1. Topical Minoxidil for the Treatment of Alopecia Areata PubMed · 2017
    2. Effectivity of Minoxidil as a Treatment for Alopecia Areata DOAJ (DOAJ: Directory of Open Access Journals) · 2013