Androgenetic Alopecia: Update on Etiology

    June 2021 in “ Dermatological reviews
    Rachita Dhurat, Sanober Burzin Daruwalla
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    TLDR AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
    This document provides an update on the causes of androgenetic alopecia (AGA), the most common form of hair loss in both men and women. AGA is influenced by genetics, androgens, and age, with dihydrotestosterone (DHT) playing a key role in miniaturizing hair follicles. The condition is caused by interactions among several genes and environmental factors, and a polygenic mode of inheritance is more likely than previously thought. Other factors that contribute to AGA include microinflammation, oxidative stress, and environmental factors. The document also covers treatment options such as medications and hair transplantation.
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