Androgenetic Alopecia: Update on Etiology

    March 2021 in “ Dermatological reviews ”
    Rachita Dhurat, Sanober Burzin Daruwalla
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    TLDR AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
    This document provides an update on the causes of androgenetic alopecia (AGA), the most common form of hair loss in both men and women. AGA is influenced by genetics, androgens, and age, with dihydrotestosterone (DHT) playing a key role in miniaturizing hair follicles. The condition is caused by interactions among several genes and environmental factors, and a polygenic mode of inheritance is more likely than previously thought. Other factors that contribute to AGA include microinflammation, oxidative stress, and environmental factors. The document also covers treatment options such as medications and hair transplantation.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 11 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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      in Progress Pictures  145 upvotes 10 months ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community 6 months on dutast and minoxodil, hair growing like weeds now!

      in Progress Pictures  601 upvotes 1 week ago
      A woman experienced significant hair regrowth after six months of using dutasteride and minoxidil, despite initial hair loss due to androgenetic alopecia. She reported minimal side effects and highlighted the effectiveness of these treatments for women, despite doctors' hesitancy to prescribe them.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 9 months ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

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