Androgenetic Alopecia: Update on Etiology

    March 2021 in “ Dermatological reviews
    Rachita Dhurat, Sanober Burzin Daruwalla
    Image of study
    TLDR AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
    This document provides an update on the causes of androgenetic alopecia (AGA), the most common form of hair loss in both men and women. AGA is influenced by genetics, androgens, and age, with dihydrotestosterone (DHT) playing a key role in miniaturizing hair follicles. The condition is caused by interactions among several genes and environmental factors, and a polygenic mode of inheritance is more likely than previously thought. Other factors that contribute to AGA include microinflammation, oxidative stress, and environmental factors. The document also covers treatment options such as medications and hair transplantation.
    Discuss this study in the Community →

    Research cited in this study

    41 / 41 results

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  135 upvotes 2 months ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

      community Does finasteride/dutasteride reverse aging?

      in Chat  45 upvotes 1 month ago
      Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

    Related Research

    6 / 6 results