TLDR Botulinum toxin has potential for treating various skin conditions and improving wound healing.
The 2018 review article explored the diverse effects of botulinum neurotoxins (BoNTs), especially BoNT/A, on non-neuronal and nonmuscular cells, including those in the skin. It highlighted BoNT/A's potential in dermatology for treating hyperhidrosis, skin diseases, aiding in wound healing, and providing anti-aging benefits. The toxin's anti-inflammatory and anti-cancer properties were also noted. The document reported that BoNT/A has been effective in reducing sebum production and pore size in oily skin, improving quality of life for patients with painful skin conditions, and showing therapeutic activity in various forms of hair loss and skin disorders. Clinical trials are underway for conditions like alopecia areata, scarring, and psoriasis. Despite some undesirable effects, the wide range of BoNT's biological impacts on human cells suggests significant potential for future medical applications.
53 citations,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
12 citations,
August 2015 in “Plastic Surgery” Botulinum toxin may help reduce skin flap damage caused by cigarette smoke.
17 citations,
August 2014 in “Journal of Craniofacial Surgery” Botulinum toxin-A reduces wound and skin graft contraction.
50 citations,
November 2010 in “Plastic and Reconstructive Surgery” Botox increased hair count in men with baldness and might work by improving scalp blood flow.
26 citations,
April 2006 in “Cephalalgia” Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.
53 citations,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
Botulinum toxin shows promise for treating scalp sweating but not for hair growth.
51 citations,
October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
March 2022 in “IntechOpen eBooks” Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.
16 citations,
March 2022 in “Archives of Toxicology” Botulinum and tetanus neurotoxins are better understood now, with updated information on their effects and treatment.
