Toxicology and Pharmacology of Botulinum and Tetanus Neurotoxins: An Update

Botox in scalp muscles is being discussed as a potential hair loss treatment. Minoxidil, finasteride, and RU58841 are also mentioned as treatments.

The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.

Botox injections may be more effective than finasteride for hair growth by reducing scalp tension. The discussion also suggests choosing FUE over FUT due to potential loss of scalp elasticity with FUT.

Botox may help with hair loss by reducing muscle tension and inflammation, potentially lowering DHT levels. Regular sessions might be needed, and it could also help with migraines.

The conversation discusses updates on hair loss treatments, specifically GT20029, PP405, and a rumored injectable peptide from UT. GT20029 is seen as a promising treatment expected within 5-7 years.