Androgenetische Alopezie
January 2004
in “
Der Hautarzt
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Research cited in this study
66 / 66 resultsresearch Efficacy and Tolerability of Finasteride 1 mg in Men Aged 41 to 60 Years with Male Pattern Hair Loss
Finasteride 1 mg significantly improves hair growth in men aged 41 to 60 with male pattern hair loss.
research Analysis of Genetic Polymorphisms of Steroid 5α-Reductase Type 1 and 2 Genes in Korean Men with Androgenetic Alopecia
Gene differences may affect baldness treatment response in Korean men.
research Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia
Steroidogenic isoenzymes may help improve treatments for common hair loss.
research Hair Loss in Women with Hyperandrogenism: Four Cases Responding to Finasteride
Finasteride improves hair loss in women with hyperandrogenism.
research A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men
5% minoxidil works better for hair growth and density, with minor irritation.
research 17α‐estradiol induces aromatase activity in intact human anagen hair follicles ex vivo
17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.
research Comparative Efficacy of Various Treatment Regimens for Androgenetic Alopecia in Men
Best hair growth results from combining finasteride and minoxidil.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Effects of Minoxidil 2% vs. Cyproterone Acetate Treatment on Female Androgenetic Alopecia: A Controlled, 12-Month Randomized Trial
Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.
research Long-Term Multinational Experience with Finasteride 1 mg in the Treatment of Men with Androgenetic Alopecia
Finasteride 1 mg/day for five years effectively improves hair growth and slows hair loss in men with male pattern baldness, and is safe for long-term use.
research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Treatment with Finasteride, 1 mg, Daily
Finasteride increases hair weight and count in men with hair loss.
research Finasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins
Finasteride effectively treats male pattern hair loss without serious side effects.
research Effects of Finasteride on Apoptosis and Regulation of the Human Hair Cycle
Finasteride helps hair growth by decreasing cell death in hair follicles.
research Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla
The study explored the role of steroid sulfatase (STS) in human hair follicles, particularly its concentration in the dermal papilla, and its potential link to androgenetic alopecia (AGA). It was found that STS is primarily located in the dermal papilla, where it converts dehydroepiandrosterone sulfate (DHEAS) to 5α-dihydrotestosterone (5α-DHT), a key androgen in hair growth regulation and AGA development. The study involved scalp biopsies from 20 healthy volunteers and beard hair follicles from 4 men. It demonstrated that STS activity could be inhibited by estrone-3-O-sulfamate, suggesting that STS inhibitors could be potential treatments for androgen-dependent hair disorders like AGA.
research Influence of estrogens on the androgen metabolism in different subunits of human hair follicles.
Estrogens can reduce DHT production in hair follicles, but are less effective than finasteride and progesterone.
research TrichoScan: Combining Epiluminescence Microscopy With Digital Image Analysis for the Measurement of Hair Growth In Vivo
TrichoScan accurately measures hair growth and showed improved hair counts and thickness after finasteride treatment.
research Polymorphism of the Androgen Receptor Gene is Associated with Male Pattern Baldness
research Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia
Finasteride doesn't effectively treat hair loss in postmenopausal women.
research Vertex Balding, Plasma Insulin-Like Growth Factor 1, and Insulin-Like Growth Factor Binding Protein 3
Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.
research Androgenetic Alopecia in Heterozygous Carriers of a Mutation in the Human Hairless Gene
Mutation in hairless gene may increase hair loss risk.
research An X-Linked Gene Involved in Androgenetic Alopecia: A Lesson to Be Learned from Adrenoleukodystrophy
Gene linked to common hair loss found, may lead to new treatments.
research Improvement in Androgenetic Alopecia in 53-76-Year-Old Men Using Oral Finasteride
Finasteride increases hair count in middle-aged and elderly men without causing sexual dysfunction.
research Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women
Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.
research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment
Minoxidil increases hair weight and count temporarily in men with hair loss.
research Finasteride, 1 mg (Propecia), Is the Optimal Dose for the Treatment of Men With Male Pattern Hair Loss
research Management of Androgenetic Alopecia
Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.
research Absence of Male-Pattern Baldness in Men with X-Linked Recessive Ichthyosis?
Men with X-linked recessive ichthyosis may not experience typical male-pattern baldness.
research Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factors in Response to Testosterone Unlike Scalp Cells
Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.
research Finasteride in the Treatment of Men with Androgenetic Alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research Androgen Receptor Polymorphisms (CAG Repeat Lengths) in Androgenetic Alopecia, Hirsutism, and Acne
Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.
research Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes
research Hair Regrowth
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research Evaluation of RU58841 as an Anti-Androgen in Prostate PC3 Cells and a Topical Anti-Alopecia Agent in the Bald Scalp of Stumptailed Macaques
RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect
Minoxidil boosts hair growth by activating PGHS-1.
research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia
Too much androgen can cause hair loss; finasteride may help.
research Message of nexin 1, a serine protease inhibitor, is accumulated in the follicular papilla during anagen of the hair cycle
research Androgenetic Alopecia: An Autosomal Dominant Disorder
Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
research The Effects of Finasteride on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques
Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
research Mechanism of Action of Androgen in Hair Follicles
Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
research Immunocytochemical Localization of Androgen Receptors in the Scalp of the Stumptail Macaque Monkey, a Model of Androgenetic Alopecia
Androgen receptors found in monkey scalps, similar to humans, affect hair growth.
research RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia, and Hirsutism
RU 58841 may treat acne, hair loss, and excessive hair growth.
research Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and Female Control Subjects
Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.
research The Psychological Effects of Androgenetic Alopecia in Men
Hair loss can cause low self-esteem, anxiety, and depression in men.
research Female Androgenetic Alopecia: A Review
research Minoxidil Specifically Decreases the Expression of Lysine Hydroxylase in Cultured Human Skin Fibroblasts
Minoxidil reduces lysine hydroxylase in skin cells.
research Cultured Dermal Papilla Cells From Androgen-Dependent Human Hair Follicles Contain More Androgen Receptors Than Those From Non-Balding Areas Of Scalp
Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.
research Hair Growth Effects of Oral Administration of Finasteride, a Steroid 5 Alpha-Reductase Inhibitor, Alone and in Combination with Topical Minoxidil in the Balding Stumptail Macaque
Finasteride and minoxidil together promote hair growth better than either alone.
research Reduced Linear Hair Growth Rates of Vellus and Terminal Hairs Produced by Human Balding Scalp Grafted onto Nude Mice
Balding scalps slow down hair growth.
research Psychological Characteristics of Women with Androgenetic Alopecia: A Controlled Study
Women with AGA often face anxiety, depression, and low self-esteem; psychological support is important.
research Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles
Minoxidil sulfate stimulates hair growth.
research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers
Finasteride safely lowers DHT levels without affecting testosterone.
research Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus
Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
research The Effect of Cyproterone Acetate on Hair Roots and Hair Shaft Diameter in Androgenetic Alopecia in Females
Cyproterone acetate effectively treats female hair loss by increasing healthy hair and decreasing unhealthy hair, but doesn't change hair thickness.
research The Effect of Testosterone, Cyproterone Acetate, and Minoxidil on Hair Loss in Androgenetic Alopecia Mouse
The mouse model could be useful for baldness research and testing treatments like testosterone, cyproterone acetate, and minoxidil.
research Topical Minoxidil in Male Pattern Baldness: Effects of Discontinuation of Treatment
Stopping minoxidil treatment resumes balding; continuous use needed for results.
research Treatment of Female Androgenetic Alopecia With Cimetidine
A drug called cimetidine can help treat hair loss in women by blocking androgen receptors. However, it's not the first choice and needs more research.
research Action of Topical Minoxidil in the Bald Stump-Tailed Macaque
Minoxidil promotes hair growth but stops working when discontinued.
research Dose-Response Study of Topical Minoxidil in Male Pattern Baldness
Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
research The inheritance of common baldness: Two B or not two B ?
research Topical Minoxidil for Hair Regrowth
5% minoxidil helps hair regrowth in androgenic alopecia.
research Effective Medical Treatment for Common Baldness in Women
Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
research Minoxidil Stimulates Cutaneous Blood Flow in Human Balding Scalps: Pharmacodynamics Measured by Laser Doppler Velocimetry and Photopulse Plethysmography
Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
research Treatment of Hirsutism, Acne, and Alopecia with Cyproterone Acetate
Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.
research Minoxidil for Severe Hypertension After Failure of Other Hypotensive Drugs
Minoxidil effectively controls blood pressure in severe cases, but has serious side effects and causes hair growth in women.
research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex
Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.
Related Research
8 / 8 results
research Hair Loss (Alopecia or Baldness)
Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.
research Treatments of Hereditary Hair Loss (Alopecia)
Some treatments like minoxidil, finasteride, and surgery can help with hereditary hair loss.
research Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells
Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
research Hair Disorders Associated With Anticancer Agents
Some cancer treatments cause different types of hair loss, but scalp cooling can help prevent it.
research Protection Against Chemotherapy-Induced Alopecia: Targeting ATP-Binding Cassette Transporters in the Hair Follicle
Increasing ABC transporters in hair follicles may prevent chemotherapy-induced hair loss.
research Pathobiology of Chemotherapy-Induced Hair Loss
Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
research Towards a Molecular Understanding of Hair Loss and Its Treatment
Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.