An X-Linked Gene Involved in Androgenetic Alopecia: A Lesson to Be Learned from Adrenoleukodystrophy

January 2000 in “ Dermatology ”

A. C. König, Rudolf Happle, E. Tchitcherina, Juergen A. Schaefer, P. Sokolowski, Werner Köhler, Rolf-Dieter Hoffmann

androgenetic alopecia AGA X-linked gene adrenoleukodystrophy ALD male pattern baldness

TLDR Gene linked to common hair loss found, may lead to new treatments.

A new study has discovered an X-linked gene that may be involved in the development of androgenetic alopecia (AGA), a common form of hair loss in men. The gene is similar to the one responsible for adrenoleukodystrophy (ALD), a rare genetic disorder that affects the nervous system. This discovery could potentially lead to new treatments for AGA. The study highlights the importance of studying rare genetic disorders to gain insights into more common conditions like androgenetic alopecia.

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community Why balding gets worse in every generation?

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community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

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community Why is it that low testosterone causes hair loss as well? How can I be balding?

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community UPDATE: The theory that explains everything. Please help me make this big!

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Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

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