Absence of Male-Pattern Baldness in Men with X-Linked Recessive Ichthyosis?

January 1999 in “ Dermatology ”

Rudolf Happle, R. Hoffmann

X-linked recessive ichthyosis steroid sulfatase androgenetic alopecia androgen metabolism

TLDR Men with X-linked recessive ichthyosis may not experience typical male-pattern baldness.

The document hypothesized that men with X-linked recessive ichthyosis (XRI), a condition caused by a deficiency of steroid sulfatase, did not exhibit androgenetic alopecia or only developed mild forms of this type of hair loss. This hypothesis was based on the role of steroid sulfatase in androgen metabolism. The document suggested that clinical studies were needed to determine if this hypothesis could be supported.

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Research cited in this study

3 / 3 results

research Androgen Metabolism as It Affects Hair Growth in Androgenetic Alopecia

143 citations , October 1996 in “Dermatologic Clinics”

Too much androgen can cause hair loss; finasteride may help.

research The Ichthyoses: A Guide to Clinical Diagnosis, Genetic Counseling and Therapy

179 citations , December 1989 in “Medical Entomology and Zoology”

Effective management of ichthyoses requires genetic counseling and appropriate treatments.

research Serum elevation of dehydroepiandrosterone sulfate associated with male pattern baldness in young men

52 citations , March 1987 in “Journal of the American Academy of Dermatology”

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research Absence of Male-Pattern Baldness in Men with X-Linked Recessive Ichthyosis?

9 citations , January 1999 in “Dermatology”

Men with X-linked recessive ichthyosis may not experience typical male-pattern baldness.