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    Building and Maintaining the Skin

    October 2021 in “ Cold Spring Harbor Perspectives in Biology ”
    Ya‐Chieh Hsu, Elaine Fuchs
    Studysummary This review discusses the interactions and signals affecting skin stem cells and their environments but reports no new experimental results; the authors highlight the need for understanding these processes to enhance tissue rejuvenation and repair.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 44

    1. Bacteria Induce Skin Regeneration via IL-1β Signaling Cell Host & Microbe · 2021
    2. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence Nature · 2021
    3. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020
    4. Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells Nature · 2020
    5. Lymphatic Vessels Interact Dynamically with the Hair Follicle Stem Cell Niche During Skin Regeneration In Vivo The EMBO Journal · 2019
    6. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019
    7. Choreographing Immunity in the Skin Epithelial Barrier Immunity · 2019
    8. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Cell · 2019
    9. Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing Nature Communications · 2018
    10. External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway Proceedings of the National Academy of Sciences of the United States of America · 2018
    11. Quiescent Tissue Stem Cells Evade Immune Surveillance Immunity · 2018
    12. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling During Hair Follicle Stem Cell Lineage Progression Cell stem cell · 2018
    13. Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties Nature cell biology · 2017
    14. Identification of Hair Shaft Progenitors That Create a Niche for Hair Pigmentation Genes & development · 2017
    15. Epithelial-Mesenchymal Micro-Niches Govern Stem Cell Lineage Choices Cell · 2017
    16. Defining Stem Cell Dynamics and Migration During Wound Healing in Mouse Skin Epidermis Nature Communications · 2017
    17. Regeneration of Fat Cells from Myofibroblasts During Wound Healing Science · 2017
    18. Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT Signaling Axis Cell Stem Cell · 2016
    19. Hair Follicles’ Transit-Amplifying Cells Govern Concurrent Dermal Adipocyte Production Through Sonic Hedgehog Genes & Development · 2016
    20. EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling Cell Reports · 2016
    21. Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations Cell · 2015
    22. Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells PLoS Biology · 2014
    23. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    24. Calcineurin/NFATc1 Signaling Links Skin Stem Cell Quiescence to Hormonal Signaling During Pregnancy and Lactation Genes & Development · 2014
    25. Mechanisms Regulating Skin Immunity and Inflammation Nature Reviews Immunology · 2014
    26. Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors Proceedings of the National Academy of Sciences of the United States of America · 2014
    27. In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators Nature Cell Biology · 2014
    28. Dedifferentiation of Committed Epithelial Cells Into Stem Cells In Vivo Nature · 2013
    29. Spatial Organization Within a Niche as a Determinant of Stem-Cell Fate Nature · 2013
    30. Fgf9 From Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding Nature Medicine · 2013
    31. Perivascular Hair Follicle Stem Cells Associate With a Venule Annulus Journal of Investigative Dermatology · 2013
    32. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    33. Shh Maintains Dermal Papilla Identity and Hair Morphogenesis via a Noggin–Shh Regulatory Loop Genes & Development · 2012
    34. A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis Nature Reviews Molecular Cell Biology · 2012
    35. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012
    36. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    37. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    38. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    39. The Basement Membrane Of Hair Follicle Stem Cells Is A Muscle Cell Niche Cell · 2011
    40. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    41. Prolactin Delays Hair Regrowth in Mice Journal of Endocrinology · 2006
    42. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    43. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor Alpha Is Checked by ER Beta Signaling Endocrinology · 2005
    44. Estrogen Receptor Alpha, But Not Estrogen Receptor Beta, Is Involved in the Regulation of Hair Follicle Cycling and Epidermis Thickness in Male Mice Journal of Investigative Dermatology · 2002

    Related research 1

    1. 25 Years of Epidermal Stem Cell Research Journal of Investigative Dermatology · 2012