2′-Fucosyllactose Alleviates Hair Loss in Testosterone-Induced Androgenic Alopecia Mice

    January 2025 in “ Journal of Food Biochemistry ”
    So‐Hyun Park, Eunyoung Lee, Daedong Kim, Jongwon Yoon, Seon-Min Jeon, Young‐Ha Song, J Bang, Chang Hwa Jung
    Image of study
    TLDR 2′‐Fucosyllactose reduces hair loss and promotes hair growth in mice.
    The study explored the effects of 2′‐Fucosyllactose (2′‐FL), a component of human milk oligosaccharides, on androgenic alopecia (AGA) in a testosterone-induced mouse model. The administration of 2′‐FL significantly reduced hair loss and increased hair length and thickness. It achieved this by enlarging hair follicle size, enhancing growth factor expression, and activating β‐catenin signaling through AKT and ERK pathways. Additionally, 2′‐FL suppressed apoptosis signaling and inflammatory cytokines in the skin of AGA mice, highlighting its potential as a therapeutic agent for AGA.
    Discuss this study in the Community →

    Research cited in this study

    36 / 36 results

    Related Community Posts Join

    6 / 1000+ results

      community 2.5 months in (guess it’s time to grow it)

      in Progress Pictures  89 upvotes 2 days ago
      The user experienced significant hair growth using topical minoxidil 5%, finasteride 0.1%, and a 0.5 mm dermaroller weekly. They reported no side effects and are pleased with the results after 2.5 months.

      community 2 Month progress, is this significant change?

      in Progress Pictures  10 upvotes 1 week ago
      A user in their 20s is experiencing hair growth after two months of using minoxidil and finasteride, focusing on the hairline and temple areas. They also addressed vitamin deficiencies (B12, D3, and iron) and are considering additional treatments like derma stamping.

      community 2-3 year progress finasteride and minoxidil

      in Is this regrowth?  104 upvotes 2 weeks ago
      The conversation discusses hair regrowth progress using finasteride and minoxidil over 2-3 years, with mixed opinions on the results. Some users note progress, while others are skeptical, and there is a side discussion about potential side effects of finasteride.

      community 2 months consistent minoxidil 5% progress.

      in Progress Pictures  69 upvotes 2 weeks ago
      A user shared their 2-month progress using 5% minoxidil and microneedling for hair loss, noting no significant changes yet. The discussion includes opinions on minoxidil, finasteride, and personal experiences with hair loss treatments.

      community 2 months on fin, 50 days on min + microneedling

      in Progress Pictures  68 upvotes 2 weeks ago
      A 32-year-old is using finasteride, oral and topical minoxidil, microneedling, and keto shampoo to treat hair loss, noticing healthier hair and new tiny hairs on previously bald areas. They are hopeful for more visible results in the coming months and encourage others to try the treatment.

    Related Research

    7 / 7 results