Akkermansia Muciniphila Promotes Testosterone-Mediated Hair Growth Inhibition in Mice

    October 2023 in “ FASEB bioAdvances ”
    E. H. Lee, Dae‐Dong Kim, Hyo‐Deok Seo … Chang Hwa Jung
    Studysummary This study investigated the effects of Akkermansia muciniphila on testosterone-induced hair growth inhibition in mice, finding that both live and pasteurized forms significantly encouraged hair growth and increased hair follicle size and growth factor levels compared to testosterone treatment alone.
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    Research cited in this study 11

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    4. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    5. Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss International Journal of Molecular Sciences · 2020
    6. A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia Stem Cells Translational Medicine · 2020
    7. M2 Macrophages Promote Wound-Induced Hair Neogenesis Journal of Dermatological Science · 2018
    8. Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia Through Overgrowth of Lactobacillus Murinus in Mice Cell Reports · 2017
    9. Effect of Sinapic Acid on Hair Growth Promotion in Human Hair Follicle Dermal Papilla Cells via Akt Activation Archives of Dermatological Research · 2017
    10. Promotion of Anagen, Increased Hair Density, and Reduction of Hair Fall in a Clinical Setting Following Identification of FGF5-Inhibiting Compounds via a Novel 2-Stage Process Clinical, Cosmetic and Investigational Dermatology · 2017
    11. Finasteride Drugs · 1999