Effects of Camellia Oleifera Seed Shell Polyphenols and 1,3,6-Tri-O-Galloylglucose on Androgenic Alopecia via Inhibiting 5α-Reductase and Regulating Wnt/β-Catenin Pathway

    July 2024 in “ Fitoterapia ”
    Qi Ru, Kun Huang, Robert K. Yu, Xiaojiang Wu, Jianfu Shen
    TLDR Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.
    The study explored the impact of Camellia oleifera seed shell polyphenols (CSSP) and 1,3,6-tri-O-galloylglucose (TGG) on androgenic alopecia (AGA) in mice. Results showed that CSSP and TGG alleviated alopecia by inhibiting 5α-reductase and regulating the Wnt/β-catenin pathway, leading to reduced androgen levels and prolonged hair growth. These findings indicate that CSSP and TGG could be promising treatments for AGA by targeting these specific pathways.
    Discuss this study in the Community →

    Related Community Posts Join

    4 / 4 results

      community Why is no one talking about redensyl?

      in Question  57 upvotes 4 years ago
      Exploring the effectiveness of redensyl, a hair loss treatment, compared to minoxidil and finasteride. People shared experiences using redensyl and products containing it, such as The Ordinary Hair Serum.

      community Any young women losing hair that have tried microneedling and oils?

      in Microneedling  32 upvotes 4 years ago
      A 25-year-old woman is experiencing hair loss and has started microneedling with a 0.5mm roller, applying a mix of essential oils overnight. She questions whether to switch to a 1.5mm roller and the best order for her routine, while a reply suggests using Minoxidil for better results.

      community This serum outperformed Minoxidil in a recent study. Please debunk

       23 upvotes 5 years ago
      A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

    Related Research

    9 / 9 results