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research Effects of Camellia Oleifera Seed Shell Polyphenols and 1,3,6-Tri-O-Galloylglucose on Androgenic Alopecia via Inhibiting 5α-Reductase and Regulating Wnt/β-Catenin Pathway

July 2024 in “Fitoterapia”

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

139 citations , December 2020 in “Cell Stem Cell”

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

research Precision Therapeutics in Non-Scarring Alopecia: A Systemic Genomic and Pathway-Based Framework for Targeted Interventions

December 2025 in “ADMET & DMPK”

Personalized treatments for hair loss focus on specific genetic and biological pathways.

Purple Corn Extract Improves Benign Prostatic Hyperplasia by Inhibiting 5 Alpha-Reductase Type 2 and Inflammation in Testosterone Propionate-Induced Rats

research Purple Corn Extract Improves Benign Prostatic Hyperplasia by Inhibiting 5 Alpha-Reductase Type 2 and Inflammation in Testosterone Propionate-Induced Rats

2 citations , January 2025 in “Frontiers in Pharmacology”

Purple corn extract may help reduce prostate enlargement and inflammation.

research Androgenetic Alopecia and Risks of Overall and Aggressive Prostate Cancer: An Updated Systematic Review and Meta-Analysis

November 2025 in “Cancers”

Men with male pattern baldness may have a slightly higher risk of prostate cancer.

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community Occipitalis Muscle Tension Theory

in Treatment 7 upvotes 1 month ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 443 upvotes 4 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community HMI 115 Phase 2 - Leaked pics from Discord

in Research/Science 357 upvotes 1 year ago

The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 192 upvotes 3 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

in Chat 138 upvotes 5 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

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