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    Glossary TRPV5

    protein channel that regulates calcium entry into cells

    TRPV5 is a type of protein that forms a channel in cell membranes, specifically allowing calcium ions to enter cells. This channel is crucial for maintaining calcium balance in the body, which is important for bone health and various cellular functions. In the context of hair and alopecia, proper calcium regulation can influence hair follicle health and growth.

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    Research 30 of 429

    1. Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole EMBO reports · 2021 · 28 citations
    2. TRPV Channels in Osteoarthritis: A Comprehensive Review Biomolecules · 2024 · 14 citations
    3. TRPV3 Ion Channel: From Gene to Pharmacology International Journal of Molecular Sciences · 2023 · 2 citations
    4. Localization of mechanosensitive channel TRPV4 in mouse skin Neuroscience Letters · 2003 · 123 citations
    5. Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53 Nature Genetics · 2009 · 99 citations
    6. TRPV3 as a Therapeutic Target for Itch Journal of Investigative Dermatology · 2012 · 88 citations
    7. Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes Journal of Investigative Dermatology · 2017 · 77 citations
    8. TRPV1 Function in Health and Disease Current Pharmaceutical Biotechnology · 2010 · 65 citations
    9. Influence of TRPV3 mutation on hair growth cycle in mice Biochemical and Biophysical Research Communications · 2007 · 59 citations
    10. Olmsted Syndrome Caused by a Homozygous Recessive Mutation in TRPV3 Journal of Investigative Dermatology · 2014 · 56 citations
    11. Hair Cycle Control by Vanilloid Receptor-1 (TRPV1): Evidence from TRPV1 Knockout Mice Journal of Investigative Dermatology · 2006 · 49 citations
    12. Activation of TRPV3 Inhibits Lipogenesis and Stimulates Production of Inflammatory Mediators in Human Sebocytes—A Putative Contributor to Dry Skin Dermatoses Journal of Investigative Dermatology · 2018 · 26 citations
    13. TRPV4 Is Expressed in Human Hair Follicles and Inhibits Hair Growth In Vitro Journal of Investigative Dermatology · 2018 · 25 citations
    14. Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol Journal of Biological Chemistry · 2022 · 24 citations
    15. Mechanisms of proton inhibition and sensitization of the cation channel TRPV3 The Journal of General Physiology · 2020 · 15 citations
    16. Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance Journal of Investigative Dermatology · 2021 · 12 citations
    17. Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes 2021 · 11 citations
    18. Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3 BioEssays · 2024 · 10 citations
    19. Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching 2015 · 7 citations
    20. Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice Developmental Cell · 2024 · 5 citations
    21. A combination of low-dose systemic etretinate and topical calcipotriol/betamethasone dipropionate treatment for hyperkeratosis and itching in Olmsted syndrome associated with a TRPV3 mutation Journal of dermatological science · 2017 · 5 citations
    22. Transient stimulation of TRPV4‐expressing keratinocytes promotes hair follicle regeneration in mice British Journal of Pharmacology · 2020 · 4 citations
    23. Therapeutic inhibition of keratinocyte TRPV3 sensory channel by local anesthetic dyclonine 2020 · 3 citations
    24. The Multifaceted Functions of TRPV4 and Calcium Oscillations in Tissue Repair International journal of molecular sciences · 2024 · 1 citations
    25. Cutaneous TRPV4 Potentiates the Afferent Transmission of Electroacupuncture Stimulation ACS Omega · 2026
    26. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    27. Natural phenylethanoid glycoside forsythoside A alleviates androgenetic alopecia by selectively inhibiting TRPV3 channels in mice European Journal of Pharmacology · 2025
    28. Pathogenesis and management of TRPV3-related Olmsted syndrome Frontiers in Genetics · 2024
    29. Case report: Novel p.Val306Met missense mutation in TRPV3 in a case of Olmsted syndrome accompanied by squamous cell carcinoma Frontiers in Oncology · 2024
    30. Whole genome sequencing analysis of alpaca suggests TRPV3 as a candidate gene for the suri phenotype BMC genomics · 2024