TLDR Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
The 2016 review article discussed sensitive skin, a condition marked by sensations like tightness and burning without visible skin reactions, affecting approximately 39% of Europeans, more commonly in women. It explored the potential mechanisms behind sensitive skin, including the role of cutaneous nerve fibers and the TRPV1 thermochannel, which may be involved in the skin's response to stimuli. The review also considered the impact of environmental factors and lifestyle choices on the condition. It highlighted the importance of the epidermal barrier, the cutaneous nervous system, and TRPV1 in sensitive skin's pathophysiology. The document detailed how TRPV1 activation could lead to inflammation and itch, particularly in conditions like psoriasis, and discussed the challenges in diagnosing and treating sensitive skin, suggesting mild skincare products, avoidance of triggers, and potential treatments targeting TRPV1 and probiotics. Professional dermatological advice was recommended for cases where standard treatments fail.
29 citations,
November 2013 in “Expert Review of Dermatology” Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
33 citations,
November 2012 in “JAMA Dermatology” Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.
61 citations,
October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
80 citations,
March 2008 in “Contact Dermatitis” Nearly half of the French individuals surveyed reported having a sensitive scalp, more common in women, often linked to hair loss and symptoms like itching, and triggered by factors including shampoos and pollution.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
61 citations,
October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
September 2004 in “Experimental dermatology” Melatonin directly affects mouse hair follicles and may influence hair growth.
1 citations,
November 2023 in “International journal of molecular sciences” Cannabinoids might help treat skin problems but more research is needed to be sure.
29 citations,
November 2013 in “Expert Review of Dermatology” Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
