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    GlossarySkin Barrier (Epidermal Barrier)

    outermost skin layer protecting against pathogens and moisture loss

    The skin barrier, also known as the epidermal barrier or cutaneous barrier, is the outermost layer of the skin that serves as a protective shield. It prevents the entry of harmful substances, pathogens, and excessive water loss, while also maintaining hydration and overall skin health. This barrier is primarily composed of lipids, proteins, and dead skin cells, and its integrity is crucial for preventing conditions like eczema and infections.

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 2 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Topical Dutasteride. Does it work?

      in Finasteride/Dutasteride  13 upvotes 5 months ago
      Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 8 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  187 upvotes 1 month ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.