Epidermal Vascular Endothelial Growth Factor Production Is Required for Permeability Barrier Homeostasis, Dermal Angiogenesis, and the Development of Epidermal Hyperplasia

    August 2008 in “ American Journal Of Pathology ”
    Peter M. Elias, Jack L. Arbiser, Barbara E. Brown … Kenneth R. Feingold
    Studysummary This study found that epidermal VEGF is crucial for maintaining skin barrier function in mice and may help explain psoriasis development following skin trauma due to its effects on angiogenesis and hyperplasia.
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    Research cited in this study 2

    1. Parathyroid Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin Journal of Investigative Dermatology · 2006
    2. Vascular Endothelial Growth Factor Is an Autocrine Growth Factor for Hair Dermal Papilla Cells Journal of Investigative Dermatology · 1996