The Role of Exosomes Derived from Mesenchymal Stromal Cells in Dermatology

    April 2021 in “ Frontiers in Cell and Developmental Biology ”
    María I. Quiñones-Vico, Raquel Sanabria-de la Torre, Manuel Sánchez‐Díaz, Álvaro Sierra-Sánchez, Trinidad Montero‐Vílchez, Ana Fernández‐González, Salvador Arias‐Santiago
    TLDR MSC-derived exosomes may help in skin repair and regeneration.
    The review discussed the potential of exosomes derived from mesenchymal stromal cells (MSCs) in dermatology, particularly in skin repair and regeneration. It highlighted that while MSCs are known for their regenerative and immunomodulatory properties, it is the exosomes within their secretome that may be crucial for these functions. The document aimed to compile existing data on the role of MSC-derived exosomes in various skin conditions using both in vitro and in vivo models. It also emphasized the necessity for further research to address limitations and facilitate clinical application.
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