Influence of TRPV3 Mutation on Hair Growth Cycle in Mice

    September 2007 in “ Biochemical and Biophysical Research Communications ”
    Kohei Imura, Takeshi Yoshioka, Ichiro Hikita … Tsuneaki Sakata
    Studysummary This study found that a gain-of-function mutation in the TRPV3 channel leads to altered hair development in DS-Nh mice by affecting the anagen and telogen phases, highlighting TRPV3's role in hair growth regulation.
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    Research cited in this study 4

    1. Hair Cycle Control by Vanilloid Receptor-1 (TRPV1): Evidence from TRPV1 Knockout Mice Journal of Investigative Dermatology · 2006
    2. Medical Treatment of Non-Scarring Alopecia Seminars in Cutaneous Medicine and Surgery · 2006
    3. Krtap16: Characterization of a New Hair Keratin-Associated Protein Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004
    4. Overexpression of Hoxc13 in Differentiating Keratinocytes Results in Downregulation of a Novel Hair Keratin Gene Cluster and Alopecia Development · 2001

    Related research 1

    1. Influence of TRPV3 Mutation on Hair Growth Cycle in Mice Biochemical and Biophysical Research Communications · 2007