Influence of TRPV3 Mutation on Hair Growth Cycle in Mice

September 2007 in “ Biochemical and Biophysical Research Communications ”

Kohei Imura, Takeshi Yoshioka, Ichiro Hikita, Kiyoshi Tsukahara, Tsutomu Hirasawa, Kenichi Higashino, Yoshinari Gahara, Akinori Arimura, Tsuneaki Sakata

TRPV3 hair growth cycle anagen phase telogen phase keratin-associated protein gene alopecia androgen effects skin inflammation high fever hair growth hair loss hair development

Studysummary This study found that a gain-of-function mutation in the TRPV3 channel leads to altered hair development in DS-Nh mice by affecting the anagen and telogen phases, highlighting TRPV3's role in hair growth regulation.

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