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    Glossary Keratinocyte Migration

    movement of skin cells from deeper layers to the surface

    Keratinocyte migration refers to the movement of keratinocytes, which are the primary cells in the outer layer of the skin, from the deeper layers to the surface. This process is crucial for wound healing and the regular turnover of the skin, ensuring that old or damaged cells are replaced with new ones.

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    1. Keratinocyte Growth Factor Modified Messenger RNA Accelerating Cell Proliferation and Migration of Keratinocytes Nucleic Acid Therapeutics · 2018 · 11 citations
    2. Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration Journal of Investigative Dermatology · 2023 · 8 citations
    3. Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro Human Cell · 2026
    4. 1433 Role of BNC1 in keratinocytes proliferation and migration: A critical regulator of wound healing? Journal of Investigative Dermatology · 2018
    5. Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing 2021
    6. 866 Senescent fibroblasts secretome promote tumoural initiation of normal human keratinocytes through cellular activation, enhanced migration and ECM remodelling European Journal of Cancer Supplements · 2010
    7. Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice Experimental Dermatology · 2018 · 10 citations
    8. N,N-Dimethylglycine Sodium Salt Exerts Marked Anti-Inflammatory Effects in Various Dermatitis Models and Activates Human Epidermal Keratinocytes by Increasing Proliferation, Migration, and Growth Factor Release International Journal of Molecular Sciences · 2023
    9. Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model Frontiers in Medicine · 2025 · 8 citations
    10. FAM19A5 negatively regulates cutaneous wound healing via PPARD-dependent inhibition of keratinocyte migration Scientific Reports · 2026
    11. 972 The ATP-dependent chromatin remodeler BRG1 controls epidermal keratinocytes migration during human cutaneous wound healing Journal of Investigative Dermatology · 2019
    12. SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling Journal of Investigative Dermatology · 2024 · 4 citations
    13. 1339 Casein kinase 1 inhibition in keratinocytes enhances the migration of melanocyte precursors in the hair follicle via KitL/c-Kit signaling pathway Journal of Investigative Dermatology · 2023
    14. JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing Scientific Reports · 2017 · 54 citations
    15. Exosomes derived from uMSCs promote hair regrowth in alopecia areata through accelerating human hair follicular keratinocyte proliferation and migration Cell Biology International · 2023
    16. Overexpression of mIGF-1 in Keratinocytes Improves Wound Healing and Accelerates Hair Follicle Formation and Cycling in Mice American Journal Of Pathology · 2008 · 55 citations
    17. Emerging role of ILK and ELMO2 in the integration of adhesion and migration pathways Cell Adhesion & Migration · 2012 · 10 citations
    18. α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity PloS one · 2020 · 7 citations
    19. Growth factor mimetics for skin regeneration: In vitro profiling of primary human fibroblasts and keratinocytes Archiv der Pharmazie · 2021 · 3 citations
    20. Epithelial cell migration on laminins Kölner Universitäts PublikationsServer (Universität zu Köln) · 2004
    21. Alteration of Skin Wound Healing in Keratinocyte-Specific Mediator Complex Subunit 1 Null Mice PloS one · 2014 · 20 citations
    22. Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation Theranostics · 2021 · 18 citations
    23. 1360 Regulation of bmp signalling in melanogenesis, pigment transfer and melanocyte migration Journal of Investigative Dermatology · 2018
    24. Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration Journal of Cell Science · 2013 · 3 citations
    25. GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states PLOS Genetics · 2017 · 38 citations
    26. The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells Pharmaceuticals · 2021 · 48 citations
    27. An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation EMBO Reports · 2018 · 30 citations
    28. Faculty Opinions recommendation of Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013
    29. Impact of Stat3 activation upon skin biology: A dichotomy of its role between homeostasis and diseases Journal of Dermatological Science · 2007 · 172 citations
    30. Thymosin β4 promotes angiogenesis, wound healing, and hair follicle development Mechanisms of Ageing and Development · 2003 · 118 citations