GRHL3 Binding and Enhancers Rearrange as Epidermal Keratinocytes Transition Between Functional States

    April 2017 in “ PLOS Genetics ”
    Rachel Herndon Klein, Ziguang Lin, Amelia Soto Hopkin … Bogi Andersen
    Studysummary This study found that human progenitor keratinocytes form unique complements of enhancers and super-enhancers during differentiation and migration, influencing gene expression and skin disease variant enrichment.
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    Research cited in this study 2

    1. Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice Nature · 2015
    2. Wound Repair at a Glance Journal of Cell Science · 2009

    Related research 1

    1. GRHL3 Binding and Enhancers Rearrange as Epidermal Keratinocytes Transition Between Functional States PLOS Genetics · 2017