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This article discusses using high performance liquid chromatography to optimize mobile phase composition for separating synthesis products of Finasteride, without reporting new clinical results.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

This study found differences in urinary androgen and estrogen concentrations between male pattern baldness patients treated with finasteride and healthy controls, suggesting potential biomarkers for post-finasteride syndrome.

Finasteride and minoxidil together safely and effectively increase hair growth and density for androgenetic alopecia.

The study reported that reducing finasteride particle size significantly improved its cellular permeation through prostate epithelial cells, though it had a lesser impact on systemic pharmacokinetics and tissue distribution in rats.

This study suggests that in gilthead seabream, DHT is involved in the onset of the meiotic phase of spermatogenesis and influences serum levels of E2 through regulation of aromatase activity.

In this study, the safety of finasteride in rats varied depending on dosing time, while its effectiveness on prostate weight reduction remained consistent.

This research observed that finasteride-loaded ethosomes showed improved permeation across rat skin and human cadaver scalp skin compared to unencapsulated finasteride, potentially enhancing delivery to hair follicle units.

Finasteride negatively affects fish reproduction and gonadal development.

This study found that finasteride reduced VEGF expression and microvessel density in the renal tissue of diabetic rats, suggesting its potential for treating diabetic microvascular complications.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

This study concluded that finasteride treatment did not adversely affect bone development or density in male rats, suggesting selective DHT deficiency is not harmful to the skeleton.

This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.

This study suggests that finasteride treatment in male rats can lead to changes in liver carbohydrate metabolism and may result in metabolic disruptions and liver steatosis in their offspring.

This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.

In this study, finasteride was found to potentiate stress-induced disruption in sensory gating of rats by neutralizing the increase in allopregnanolone levels after acute stress.

This study found that topical fulvestrant did not significantly improve hair growth parameters in men and postmenopausal women with androgenetic alopecia, unlike minoxidil, which was more effective in men.

Terazosin and finasteride together cause no major issues.

In this study, finasteride treatment for two years did not significantly reverse miniaturized hair follicles in men with male pattern hair loss, challenging the "reversal hypothesis" as 79 out of 113 miniaturized hairs remained unchanged.

In a clinical trial, this study found that a modified slow-release oral testosterone formulation improved pharmacokinetics, delaying serum testosterone peaks and reducing serum DHT compared to immediate-release formulations, especially when combined with finasteride.

This study reported that combined oral finasteride and topical 5% minoxidil treatment in men with male-pattern hair loss improved hair growth by initiating anagen in pre-existing but deficient follicles, yet the growth rates remained unchanged and did not normalize hair productivity.

This study found that finasteride administration in hamsters led to significant spermatogenesis reduction and seminiferous tubule atrophy compared to the control group.

This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.

This study developed two sensitive chromatographic methods for determining finasteride and tamsulosin hydrochloride in pharmaceutical forms, validated against International Conference on Harmonisation guidelines.

This study found that both finasteride and metformin effectively reduced androgen levels and insulin resistance parameters in women with PCOS, without clear evidence of one treatment being superior.

This study found that finasteride gel 0.25% significantly decreased hair growth in women with idiopathic hirsutism over six months without any reported side effects.

This study optimized and validated a dissolution test method for immediate-release finasteride capsules, highlighting the need for an official standard due to variability in commercial products.

This study found that two different 5 mg finasteride tablet formulations are bioequivalent in terms of the rate and extent of absorption in healthy volunteers.

This study concluded that finasteride 1 mg does not significantly affect the metabolism of omeprazole in young healthy Japanese male extensive or poor metabolizers for CYP2C19.

This study suggests that finasteride may inhibit the enzyme PNMT, potentially contributing to its sexual and psychological side effects.