Determination of Finasteride and Related Compounds by Reversed-Phase High Performance Liquid Chromatography: Choosing the Mobile Phase Composition

    January 1999 in “ Journal of Liquid Chromatography & Related Technologies ”
    Ilona Cendrowska, Bogusław Buszewski
    Image of study
    TLDR Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
    This document discusses the use of high performance liquid chromatography (HPLC) to detect finasteride and related compounds. The focus is on selecting the appropriate mobile phase composition for optimal results. The authors found that a mixture of acetonitrile and water with trifluoroacetic acid or methanol produced the best results for the mobile phase composition. The study aimed to find the best mobile phase composition for detecting all nine compounds of Finasteride synthesis using RP HPLC. The recommended method had good repeatability and linearity for Finasteride, with detection limits ranging from 0.3-1.1 ng for all solutes.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community CB-03-01: I need help

      in Treatment  7 upvotes 3 years ago
      The user stopped using finasteride and RU58841 and is considering CB-03-01 for androgenic alopecia but is concerned about the cost and effectiveness, especially at a lower dose than in clinical trials. They are also using minoxidil, micro-needling, and nizoral shampoo but are unsure about the correct application method for CB-03-01.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

    Related Research

    1 / 1 results