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    Placebo-Controlled Dose-Effect Studies with Topical Minoxidil 2% or 5% in Male-Patterned Hair Loss Treated with Oral Finasteride Employing an Analytical and Exhaustive Study Protocol

    January 2020 in “ Skin Research and Technology
    D. Van Neste
    Studysummary This study reported that combined oral finasteride and topical 5% minoxidil treatment in men with male-pattern hair loss improved hair growth by initiating anagen in pre-existing but deficient follicles, yet the growth rates remained unchanged and did not normalize hair productivity.
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    Research cited in this study 15

    1. Viable Terminal Scalp Hair Follicles Are Necessary and Sufficient for Clinical Efficacy of Finasteride in Male Pattern Hair Loss Skin Research and Technology · 2019
    2. Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect Skin Research and Technology · 2019
    3. A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth Experimental Dermatology · 2018
    4. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    5. Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients Dermatologic Therapy · 2015
    6. Why Care About Linear Hair Growth Rates? A Study Using In Vivo Imaging and Computer-Assisted Image Analysis After Manual Processing in Unaffected Male Controls and Men with Male Pattern Hair Loss European Journal of Dermatology · 2014
    7. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    8. From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber Journal of Investigative Dermatology · 2009
    9. Exogen Hair Characterization in Human Scalp Skin Research and Technology · 2007
    10. Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride Skin Pharmacology and Physiology · 2006
    11. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    12. Finasteride Treatment May Not Prevent Telogen Effluvium After Minoxidil Withdrawal Archives of Dermatology · 2003
    13. Current and Novel Methods for Assessing Efficacy of Hair Growth Promoters in Pattern Hair Loss Journal of The American Academy of Dermatology · 2003
    14. Comparative Efficacy of Various Treatment Regimens for Androgenetic Alopecia in Men Journal of Dermatology · 2002
    15. Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Treatment with Finasteride, 1 mg, Daily Journal of The American Academy of Dermatology · 2002

    Related research 9

    1. Pediatric Androgenetic Alopecia: An Updated Review Journal der Deutschen Dermatologischen Gesellschaft · 2023
    2. Complex Approach to the Treatment of Androgenetic Alopecia in Male Persons with a Poor Prognosis of the Disease Voennaâ medicina · 2022
    3. Modulation of Hair Growth Promoting Effect by Natural Products Pharmaceutics · 2021
    4. Male Androgenetic Alopecia CRC Press eBooks · 2021
    5. Comparison of QR 678 and QR 678 Neo as Monotherapy and Combination Therapy with 5% Minoxidil Solution and Oral Finasteride in the Treatment of Male Androgenetic Alopecia—Which Is Better? Journal of Cosmetic Dermatology · 2021
    6. Androgenetic Alopecia and Its Remedies: A Review Journal of drug discovery and therapeutics · 2014
    7. Controversy: Is There a Role for Adjuvants in the Management of Male Pattern Hair Loss? PubMed · 2010
    8. Treatment Of Hair Loss วารสารเภสัชวิทยา (Thai Journal of Pharmacology) · 2000
    9. Current Management of Androgenetic Alopecia in Men PubMed · 1999