Viable Terminal Scalp Hair Follicles Are Necessary and Sufficient for Clinical Efficacy of Finasteride in Male Pattern Hair Loss

    June 2019 in “ Skin Research and Technology ”
    D. Van Neste
    Studysummary In this study, finasteride treatment for two years did not significantly reverse miniaturized hair follicles in men with male pattern hair loss, challenging the "reversal hypothesis" as 79 out of 113 miniaturized hairs remained unchanged.
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    Research cited in this study 9

    1. Why Care About Linear Hair Growth Rates? A Study Using In Vivo Imaging and Computer-Assisted Image Analysis After Manual Processing in Unaffected Male Controls and Men with Male Pattern Hair Loss European Journal of Dermatology · 2014
    2. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    3. Exogen Hair Characterization in Human Scalp Skin Research and Technology · 2007
    4. Validation of Scalp Coverage Scoring Methods for Scalp Hair Loss in Male Pattern Hair Loss (Androgenetic Alopecia) Skin Research and Technology · 2006
    5. Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride Skin Pharmacology and Physiology · 2006
    6. Validation and Clinical Relevance of a Novel Scalp Coverage Scoring Method Skin Research and Technology · 2003
    7. Finasteride and the Hair Cycle Journal of The American Academy of Dermatology · 2000
    8. Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women Journal of Investigative Dermatology Symposium Proceedings · 1999
    9. Finasteride in the Treatment of Men with Frontal Male Pattern Hair Loss Journal of The American Academy of Dermatology · 1999

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    2. Viable Terminal Scalp Hair Follicles Are Necessary and Sufficient for Clinical Efficacy of Finasteride in Male Pattern Hair Loss Skin Research and Technology · 2019
    3. Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect Skin Research and Technology · 2019
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