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    Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year

    March 2020 in “ Metabolites ”
    Yura Lee, Eunju Im, Haksoon Kim … Bong Hyun Chung
    Studysummary This study found differences in urinary androgen and estrogen concentrations between male pattern baldness patients treated with finasteride and healthy controls, suggesting potential biomarkers for post-finasteride syndrome.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 19

    1. Altered Polyamine Profiling in the Hair of Patients with Androgenic Alopecia and Alopecia Areata Journal of Dermatology · 2019
    2. Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry Journal of Chromatography B · 2019
    3. Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients The Journal of Steroid Biochemistry and Molecular Biology · 2017
    4. Prevalence of Nutritional Deficiencies in Hair Loss Among Indian Participants: Results of a Cross-Sectional Study International Journal of Trichology · 2017
    5. Patients Treated for Male Pattern Hair Loss with Finasteride Show Altered Levels of Neuroactive Steroids in Cerebrospinal Fluid and Plasma After Discontinuation The Journal of Steroid Biochemistry and Molecular Biology · 2014
    6. Organic Causes of Erectile Dysfunction in Men Under 40 Urologia Internationalis · 2013
    7. Neuroactive Steroid Levels Are Modified in Cerebrospinal Fluid and Plasma of Post-Finasteride Patients Showing Persistent Sexual Side Effects and Anxious/Depressive Symptomatology The Journal of Sexual Medicine · 2013
    8. Hair Steroid Profiling Reveals Racial Differences in Male Pattern Baldness Between Korean and Caucasian Populations ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2012
    9. Gas Chromatography/Mass Spectrometry Based Hair Steroid Profiling May Reveal Pathogenesis in Hair Follicles of the Scalp Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry · 2011
    10. Inhibition of Human Steroid 5β-Reductase (AKR1D1) by Finasteride and Structure of the Enzyme-Inhibitor Complex Journal of Biological Chemistry · 2009
    11. Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration British Journal of Dermatology · 2006
    12. Finasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins PubMed · 2002
    13. Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Treatment with Finasteride, 1 mg, Daily Journal of The American Academy of Dermatology · 2002
    14. Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness Journal of Investigative Dermatology · 2001
    15. Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia British Journal of Dermatology · 2000
    16. The Effects of Finasteride on Scalp Skin and Serum Androgen Levels in Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1999
    17. Finasteride in the Treatment of Men with Androgenetic Alopecia Journal of The American Academy of Dermatology · 1998
    18. Effect of Finasteride on Human Testicular Steroidogenesis PubMed · 1996
    19. The Effects of Finasteride on Hair Growth, Hair Cycle Stage, and Serum Testosterone and Dihydrotestosterone in Adult Male and Female Stumptail Macaques The Journal of Clinical Endocrinology and Metabolism · 1994

    Related research 2

    1. Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year Metabolites · 2020
    2. Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Serum Gonadotropins in Normal Men The Journal of Clinical Endocrinology and Metabolism · 1992