Simultaneous Determination of Androgens and Prostaglandins in Human Urine Using Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry

    January 2019 in “ Journal of Chromatography B ”
    Eunju Im, Bark Lynn Lew, Mi Yeon Lee … Bong Chul Chung
    Studysummary This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.
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    Research cited in this study 7

    1. Hair Steroid Profiling Reveals Racial Differences in Male Pattern Baldness Between Korean and Caucasian Populations ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2012
    2. Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012
    3. Gas Chromatography/Mass Spectrometry Based Hair Steroid Profiling May Reveal Pathogenesis in Hair Follicles of the Scalp Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry · 2011
    4. Evaluation of Androgens in the Scalp Hair and Plasma of Patients with Male-Pattern Baldness Before and After Finasteride Administration British Journal of Dermatology · 2006
    5. Influence of Prostaglandin F2α and Its Analogues on Hair Regrowth and Follicular Melanogenesis in a Murine Model Experimental dermatology · 2005
    6. Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness Journal of Investigative Dermatology · 2001
    7. Epitestosterone—An Endogenous Antiandrogen? Journal of steroid biochemistry/Journal of Steroid Biochemistry · 1989