The Hair Loss Encyclopedia

Assessment of the Pharmacokinetic-Pharmacodynamic Interaction Between Terazosin and Finasteride

December 1996 in “ The Journal of Clinical Pharmacology ”

Emil Samara, Bala Hosmane, Charles Locke, Carolyn J. Eason, John M. Cavanaugh, G. Richard Granneman

terazosin finasteride Propecia

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TLDR Terazosin and finasteride together cause no major issues.

The study aimed to assess the pharmacokinetic-pharmacodynamic interaction between terazosin and finasteride. The results showed that there was little evidence of clinically relevant interaction between the drugs, except for some variability in the group receiving both drugs. The concurrent administration of multiple doses of terazosin and finasteride produced no significant clinical concern.

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Research cited in this study

3 / 3 results

Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine

research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine

9 citations , October 1993 in “The Journal of Clinical Pharmacology”

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

Finasteride

research Finasteride

86 citations , July 1993 in “Drugs”

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

High-Performance Liquid Chromatographic Method for the Determination of Finasteride in Human Plasma at Therapeutic Doses

research High-Performance Liquid Chromatographic Method for the Determination of Finasteride in Human Plasma at Therapeutic Doses

19 citations , May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications”

Reliable method detects finasteride in human plasma at low doses.