The Effect of Finasteride on Spermatogenesis of Mesocricetus Auratus

    June 2008 in “ Acta Cirurgica Brasileira
    Dimas José Araújo Vidigal, Alcino Lázaro da Silva, Luiz Marcos da Fonseca, Anilton Cesar Vasconcelos, Dilermando Fazito de Resende, Felipe Eduardo Costa Vidigal
    Image of study
    TLDR Finasteride causes sperm production decrease in Mesocricetus auratus.
    This study investigated the effect of finasteride on the spermatogenesis of adult Mesocricetus auratus. The experimental group was given finasteride for 90 days, and the results showed significant tubules atrophy and spermatogenesis reduction compared to the control group. The study highlights concerns about the use of finasteride in patients of fertile age due to its potential impact on androgen metabolism. Further investigation is needed to determine the safe dose of finasteride to be used and its administration interval.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results

      community Physician here AMA – 30M oral Fin 1-1.25 mg daily

      in Update  47 upvotes 2 years ago
      Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

      community Huberman tweet about finasteride

      in Finasteride/Dutasteride  278 upvotes 1 year ago
      The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

      community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?

      in Technology  105 upvotes 1 year ago
      The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.

      community Is this true? Is long term taking fin harmful to the liver?

      in Chat  127 upvotes 10 months ago
      The conversation discusses whether long-term use of finasteride (Fin) is harmful to the liver, with various opinions on side effects and comparisons to other substances. Specific treatments mentioned include finasteride, minoxidil (Min), and RU58841 (RU).

      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  165 upvotes 1 month ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

    Related Research

    2 / 2 results