Pharmacokinetics of Two Novel Formulations of Modified-Release Oral Testosterone Alone and With Finasteride in Normal Men With Experimental Hypogonadism

November 2010 in “ International Journal of Andrology ”

C. N. Snyder, Richard F. Clark, Ralph B. Caricofe, Mark B. Bush, Mara Y. Roth, Stephanie T. Page, William J. Bremner, John K. Amory

testosterone modified-release oral testosterone finasteride hypogonadism androgen replacement therapy Propecia

Studysummary In a clinical trial, this study found that a modified slow-release oral testosterone formulation improved pharmacokinetics, delaying serum testosterone peaks and reducing serum DHT compared to immediate-release formulations, especially when combined with finasteride.

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