Optimization of Microstructured Biodegradable Finasteride Formulation for Depot Parenteral Application

    February 2016 in “ Journal of Microencapsulation ”
    Osama M. Ahmed, Amal K. Hussein, Fatma M. Mady
    Studysummary This study found that injectable finasteride microspheres provided a sustained drug release with a minimal initial burst in albino rabbits compared to oral suspension.
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    Research cited in this study 6

    1. Chitosan-Decorated Polystyrene-b-Poly(Acrylic Acid) Polymersomes as Novel Carriers for Topical Delivery of Finasteride European Journal of Pharmaceutical Sciences · 2013
    2. Validated RP-HPLC and TLC Methods for Simultaneous Estimation of Tamsulosin Hydrochloride and Finasteride in Combined Dosage Forms Acta Pharmaceutica · 2010
    3. Male Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2010
    4. Bioequivalence of a Single 10-mg Dose of Finasteride 5-mg Oral Disintegrating Tablets and Standard Tablets in Healthy Adult Male Han Chinese Volunteers: A Randomized Sequence, Open-Label, Two-Way Crossover Study Clinical Therapeutics · 2009
    5. Finasteride in Biological Fluids: Extraction and Separation by a Graphitized Carbon Black Cartridge and Quantification by High-Performance Liquid Chromatography Journal of Chromatography B: Biomedical Sciences and Applications · 1997
    6. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology · 1995