Chitosan-Decorated Polystyrene-b-Poly(Acrylic Acid) Polymersomes as Novel Carriers for Topical Delivery of Finasteride

    November 2013 in “ European Journal of Pharmaceutical Sciences ”
    Gustavo Amadeu Micke, Ledilege Cucco Porto, Andréa Granada … Valdir Soldi
    Studysummary This study examined different polymersome systems for topical finasteride delivery and found that chitosan-decorated C7 polymersomes may enhance skin retention and provide controlled drug release compared to non-decorated systems in laboratory settings.
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    Research cited in this study 7

    1. Male Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2010
    2. Enhancement of Percutaneous Absorption of Finasteride by Cosolvents, Cosurfactant, and Surfactants Pharmaceutical Development and Technology · 2009
    3. In Vitro Percutaneous Permeation and Skin Accumulation of Finasteride Using Vesicular Ethosomal Carriers Aaps Pharmscitech · 2008
    4. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006
    5. Podophyllotoxin-Loaded Solid Lipid Nanoparticles for Epidermal Targeting Journal of controlled release · 2005
    6. Skin Permeation of Different Steroid Hormones from Polymeric Coated Liposomal Formulations European journal of pharmaceutics and biopharmaceutics · 2005
    7. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology · 1995

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    1. Chitosan-Decorated Polystyrene-b-Poly(Acrylic Acid) Polymersomes as Novel Carriers for Topical Delivery of Finasteride European Journal of Pharmaceutical Sciences · 2013