Bioequivalence of a Single 10-mg Dose of Finasteride 5-mg Oral Disintegrating Tablets and Standard Tablets in Healthy Adult Male Han Chinese Volunteers: A Randomized Sequence, Open-Label, Two-Way Crossover Study

    October 2009 in “ Clinical Therapeutics
    Lei Chen, Xuehua Jiang, Liang Huang, Ke Lan, Haiying Wang, Lina Hu, Jing Ren, Xihong Li, Qin Zou
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    TLDR Finasteride 5-mg oral disintegrating tablets and standard tablets are bioequivalent in healthy adult male Han Chinese volunteers.
    This study aimed to compare the bioequivalence of a single 10-mg dose of finasteride 5-mg oral disintegrating tablets and standard tablets in healthy adult male Han Chinese volunteers. The study found that both formulations were bioequivalent in terms of the rate and extent of absorption, but there was a significant difference in Tmax between the two formulations. The study concluded that the oral disintegrating tablets of finasteride 5-mg and standard tablets were bioequivalent in healthy adult male Han Chinese volunteers.
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