Finasteride 1 mg Has No Inhibitory Effect on Omeprazole Metabolism in Extensive and Poor Metabolizers for CYP2C19 in Japanese

September 2006 in “ European Journal of Clinical Pharmacology ”

Toshio Yasumori, Hideo Narita, T. Matsuda, Takayuki Takubo, Michio Ogawa, Mamoru Ishii, Kazuhiko Hara, Yoshio Ishii, Kikuo Okuyama, G. Fujimoto, H Ochiai, Akihiro Kano, Satoshi Hasegawa, Koji Sato, Takashi Taniguchi

finasteride CYP2C19 Propecia

Studysummary This study concluded that finasteride 1 mg does not significantly affect the metabolism of omeprazole in young healthy Japanese male extensive or poor metabolizers for CYP2C19.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

14 / 14 results

research Organic Causes of Erectile Dysfunction in Men Under 40

2152 citations , November 2013 in “Urologia Internationalis”

This study reviews the significant prevalence of organic etiologies, especially vascular causes, in erectile dysfunction among men under 40 and emphasizes thorough evaluation and consideration of treatment options like exercise and PDE-5 inhibitors.

research Finasteride in the Treatment of Japanese Men with Male Pattern Hair Loss

12 citations , October 2004 in “PubMed”

This study found that finasteride 1 mg per day improved hair growth and slowed hair loss in Japanese men with male pattern hair loss compared to lower doses and placebo.

research Efficacy and Tolerability of Finasteride 1 mg in Men Aged 41 to 60 Years with Male Pattern Hair Loss

22 citations , July 2003 in “PubMed”

This study reported that finasteride 1 mg significantly improved hair growth in men aged 41 to 60 with predominantly vertex male pattern hair loss over 24 months compared to placebo.

research Long-Term Multinational Experience with Finasteride 1 mg in the Treatment of Men with Androgenetic Alopecia

20 citations , April 2002 in “PubMed”

This study found that long-term treatment with finasteride 1 mg/day significantly improved scalp hair growth and was well tolerated in men with androgenetic alopecia over five years compared to placebo.

research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Treatment with Finasteride, 1 mg, Daily

66 citations , April 2002 in “Journal of The American Academy of Dermatology”

In this study, finasteride, 1 mg daily, significantly increased hair weight more than hair count in men with androgenetic alopecia, indicating additional factors like hair growth rate and thickness may contribute to its effectiveness.

research Finasteride Increases Anagen Hair in Men with Androgenetic Alopecia

129 citations , October 2000 in “British Journal of Dermatology”

This study found that finasteride increases anagen hair growth in men with androgenetic alopecia.

research Finasteride, 1 mg (Propecia), Is the Optimal Dose for the Treatment of Men With Male Pattern Hair Loss

15 citations , August 1999 in “Archives of Dermatology”

research Finasteride, a Type 2 5α-Reductase Inhibitor, in the Treatment of Men with Androgenetic Alopecia

32 citations , April 1999 in “Expert Opinion on Investigational Drugs”

Clinical studies reported that finasteride reduces scalp dihydrotestosterone levels and improves hair growth in men with androgenetic alopecia, supporting its role as a treatment option.

research Pharmacokinetic Interaction Between Finasteride and Terazosin, but Not Finasteride and Doxazosin

6 citations , November 1998 in “The Journal of Clinical Pharmacology”

Finasteride interacts with terazosin, but not doxazosin; caution needed.

research Finasteride in the Treatment of Men with Androgenetic Alopecia

581 citations , October 1998 in “Journal of The American Academy of Dermatology”

In male pattern hair loss, this study found that finasteride 1 mg daily significantly slowed hair loss and increased hair growth over two years compared to placebo.

research Assessment of the Pharmacokinetic-Pharmacodynamic Interaction Between Terazosin and Finasteride

6 citations , December 1996 in “The Journal of Clinical Pharmacology”

Terazosin and finasteride together cause no major issues.

research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride

93 citations , January 1996 in “Clinical Pharmacokinectics”

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

research Identification of Human Cytochrome P450 Isozymes Responsible for the In Vitro Oxidative Metabolism of Finasteride

20 citations , October 1995 in “PubMed”

This study identified CYP3A4 as a key isozyme involved in the oxidative metabolism of finasteride in human liver microsomes.

research Current Treatment of Benign Prostatic Hyperplasia

11 citations , January 1995 in “Biomedicine & pharmacotherapy”

This review discusses the use of finasteride and alpha antagonists for symptomatic benign prostatic hypertrophy and suggests current studies are evaluating combination therapies as potential non-surgical alternatives.