Current Treatment of Benign Prostatic Hyperplasia
January 1995
in “
Biomedicine & pharmacotherapy
”
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Studysummary This review discusses the use of finasteride and alpha antagonists for symptomatic benign prostatic hypertrophy and suggests current studies are evaluating combination therapies as potential non-surgical alternatives.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document reviewed the treatment of benign prostatic hyperplasia (BPH) as of 1995, highlighting that transurethral resection of the prostate (TURP) was the gold standard but left 20% of patients unsatisfied. Medical treatments included alpha-blockers, which improved symptoms but did not reduce prostate size, and finasteride, which reduced prostate volume and improved symptoms but could cause decreased libido and impotence. Studies involving 1,645 patients showed finasteride's sustained benefits over 24 months, with ongoing research into combining therapies as alternatives to surgery.
