Pharmacokinetic Interaction Between Finasteride and Terazosin, but Not Finasteride and Doxazosin
November 1998
in “
The Journal of Clinical Pharmacology
”
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Studysummary Finasteride interacts with terazosin, but not doxazosin; caution needed.
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A study examined the interaction between finasteride and two drugs used to treat benign prostatic hyperplasia (BPH) in healthy men. The study found that there was a pharmacokinetic interaction between finasteride and terazosin, but not between finasteride and doxazosin. The interaction affects the pharmacokinetics of finasteride but not terazosin. Caution should be taken when prescribing finasteride and terazosin together due to potential drug interactions. The clinical significance of this interaction is still unknown. The study involved a total of 90 healthy male volunteers.
