Pharmacokinetic Interaction Between Finasteride and Terazosin, but Not Finasteride and Doxazosin

November 1998 in “ The Journal of Clinical Pharmacology ”

Vijay Vashi, Menger Chung, James E. Hilbert, Victor B. Lawrence, Kern Phillips

TLDR Finasteride interacts with terazosin, but not doxazosin; caution needed.

A study examined the interaction between finasteride and two drugs used to treat benign prostatic hyperplasia (BPH) in healthy men. The study found that there was a pharmacokinetic interaction between finasteride and terazosin, but not between finasteride and doxazosin. The interaction affects the pharmacokinetics of finasteride but not terazosin. Caution should be taken when prescribing finasteride and terazosin together due to potential drug interactions. The clinical significance of this interaction is still unknown. The study involved a total of 90 healthy male volunteers.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research The Efficacy of Terazosin, Finasteride, or Both in Benign Prostatic Hyperplasia

728 citations , August 1996 in “The New England Journal of Medicine”

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

1040 citations , October 1992 in “The New England Journal of Medicine”

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Related Community Posts Join

6 / 1000+ results

community A little inspiration for my 18 year old balders. Left is 18 year old me right one is 24 year old me. Only propecia 1 mg daily never miss it.

in Progress Pictures 172 upvotes 1 year ago

The conversation discusses the positive effects of taking finasteride (Propecia) for hair loss, with users sharing experiences of minimal side effects and improved hair growth over several years. The original poster emphasizes the importance of consistent use and mentions using Nizoral shampoo occasionally.

community Adding finasteride into stemoxydine

in Finasteride/Dutasteride 2 upvotes 10 months ago

The conversation discusses adding finasteride (Propecia) to a liquid containing stemoxydine for hair loss treatment. The user is inquiring about the effectiveness of this combination.

community 5 months topical minoxidil and 1 mg oral fin, identical hair lengths.

in Progress Pictures 499 upvotes 6 months ago

A 25-year-old shared impressive hair regrowth results after 5 months using 5% topical minoxidil (Rogaine and Kirkland) and 1 mg oral finasteride (Propecia), with no shedding or side effects. The user applies minoxidil twice daily and finasteride once daily.

community Father trying to save his 17 year old son from MPB

in Progress Pictures 160 upvotes 3 years ago

Father assists son with hair loss using Finasteride Propecia. Son's hair improves, considers adding Minoxidil or Dutasteride for better results.

community Good hair days; finastride

in Finasteride/Dutasteride 15 upvotes 4 years ago

The user expresses positivity about managing hair loss and celebrates good hair days. They mention using finasteride (Propecia) as part of their treatment.

community If you're sitting there wondering, "I'm losing my hair, what do I do?" then read my advice here. I've been fighting the fight for 7 years, with great success. (pictures included)

in Question 107 upvotes 12 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

Related Research

1 / 1 results

research Key Clinical Trials in Benign Prostatic Hyperplasia

4 citations , January 2002

Alpha-blockers and Finasteride effectively manage BPH symptoms long-term.