TLDR Finasteride interacts with terazosin, but not doxazosin; caution needed.
A study examined the interaction between finasteride and two drugs used to treat benign prostatic hyperplasia (BPH) in healthy men. The study found that there was a pharmacokinetic interaction between finasteride and terazosin, but not between finasteride and doxazosin. The interaction affects the pharmacokinetics of finasteride but not terazosin. Caution should be taken when prescribing finasteride and terazosin together due to potential drug interactions. The clinical significance of this interaction is still unknown. The study involved a total of 90 healthy male volunteers.
728 citations,
August 1996 in “The New England Journal of Medicine” Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.
1040 citations,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
June 2017 in “Reactions Weekly” Finasteride (Propecia) may cause depression and suicidal thoughts; stop use and inform a healthcare professional if symptoms develop.
June 2024 in “Georgetown medical review” Finasteride treats hair loss but may cause low libido, erectile issues, and depression.
11 citations,
February 2004 in “Clinical and Experimental Ophthalmology” Taking Propecia might lead to the development of cataracts.
May 2020 in “International journal of molecular biology” Mutations in the AR gene cause hair thinning and loss.
8 citations,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” Hair transplantation has improved to look more natural, but managing patient expectations and using precise techniques are key for the best outcomes.
