In Vivo and In Silico Evaluation of the Ameliorative Effect of Hesperidin on Finasteride-Induced Testicular Oxidative Stress in Wistar Rats

    October 2020 in “ Toxicology Mechanisms and Methods ”
    Ebenezer Tunde Olayinka, Kayode S. Adewole
    Studysummary This study found that in male rats, hesperidin co-administration ameliorated finasteride-induced testicular toxicity by reducing oxidative stress and improving antioxidant status, sperm parameters, and enzyme activity compared to finasteride treatment alone.
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    Research cited in this study 2

    1. 5α-Reductase Inhibitors and Male Reproduction Advances in Experimental Medicine and Biology · 2017
    2. Finasteride Use in the Male Infertility Population: Effects on Semen and Hormone Parameters Fertility and Sterility · 2013

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    1. In Vivo and In Silico Evaluation of the Ameliorative Effect of Hesperidin on Finasteride-Induced Testicular Oxidative Stress in Wistar Rats Toxicology Mechanisms and Methods · 2020