Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules

April 2022 in “ International Journal of Molecular Sciences ”

Yihe Ma, Yumiao Lin, Wenting Huang, Xusheng Wang

dermal papilla cells DPC-LCs TTNPB CHIR99021 Forskolin hair-inducing capacity fibroblasts alopecia

Studysummary This study showed that treating mouse fibroblasts with TTNPB can efficiently convert them into dermal-papilla-cell-like cells with strong hair-inducing capacity, suggesting potential for hair follicle regeneration therapies.

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