The Regulatory Mechanisms of Mitophagy and Oxidative Stress in Androgenetic Alopecia

    May 2025 in “ Cellular Signalling ”
    Devi Bi, Ying Hu, Shucheng Hua … Shun Guo
    Studysummary Oxidative stress and mitophagy play key roles in hair loss, suggesting potential treatment targets.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 25

    1. Resveratrol-Loaded Versatile Nanovesicle for Alopecia Therapy via Comprehensive Strategies International Journal of Nanomedicine · 2024
    2. Oxidative Stress in Hair Follicle Development and Hair Growth: Signaling Pathways, Intervening Mechanisms and Potential of Natural Antioxidants Journal of Cellular and Molecular Medicine · 2024
    3. Autophagy Dysfunction: The Kernel of Hair Loss? Clinical Cosmetic and Investigational Dermatology · 2024
    4. Androgenetic Alopecia: A Review Nigerian Postgraduate Medical Journal · 2024
    5. Molybdenum Nanoparticles as a Potential Topical Medication for Alopecia Treatment Journal of Trace Elements in Medicine and Biology · 2023
    6. The AR/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia International Journal of Biological Sciences · 2023
    7. Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia Nano Letters · 2022
    8. 5-Bromo-3,4-Dihydroxybenzaldehyde Promotes Hair Growth Through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells Molecules · 2022
    9. Observations Suggesting a Contribution of Altered Dermal Papilla Mitochondrial Function to Androgenetic Alopecia Experimental Dermatology · 2022
    10. The Inflammatory Component of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2021
    11. Clinical Patterns of Hair Loss in Men Dermatologic Clinics · 2021
    12. Evaluation of Selected Parameters of Oxidative Stress in Patients with Androgenetic Alopecia Postepy Dermatologii I Alergologii · 2021
    13. Examination of Androgenetic Alopecia with Serum Biomarkers Journal of Cosmetic Dermatology · 2020
    14. The Impact of Oxidative Stress in Androgenic Alopecia in Women Postepy Dermatologii I Alergologii · 2020
    15. Stimulation of Hair Growth by Small Molecules That Activate Autophagy Cell reports · 2019
    16. Genetic and Molecular Aspects of Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018
    17. GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk Nature Communications · 2017
    18. Androgens and Androgen Receptor Action in Skin and Hair Follicles Molecular and Cellular Endocrinology · 2017
    19. Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond? BioEssays · 2017
    20. Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition Journal of Investigative Dermatology · 2016
    21. Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial-Mesenchymal Interactions Journal of Investigative Dermatology · 2015
    22. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    23. Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development Science Signaling · 2013
    24. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    25. Hair Growth Stimulatory Effect by a Combination of 5-Aminolevulinic Acid and Iron Ion International Journal of Dermatology · 2008