The Pathogenesis of Oxidative Stress in Androgenetic Alopecia

Androgenetic alopecia (AGA) is a prevalent form of hair loss influenced by genetic, hormonal, and environmental factors, with oxidative stress emerging as a significant contributor. Oxidative stress, characterized by an imbalance between oxidation and antioxidation, leads to the accumulation of reactive oxygen species (ROS) that damage hair follicle cells and promote hair loss. This review highlights how oxidative stress interacts with genetic factors and androgens to exacerbate hair follicle damage, offering new insights into potential treatment strategies for AGA.