Ellagic Acid Inhibits Dihydrotestosterone-Induced Ferroptosis and Promotes Hair Regeneration by Activating the Wnt/Beta-Catenin Signaling Pathway

    April 2024 in “ Journal of ethnopharmacology ”
    Hangjie Fu, Wenxia Li, Jinyuan Liu … Bin Ding
    Studysummary This study demonstrated that ellagic acid promoted hair regrowth in a DHT-induced androgenic alopecia mouse model by inhibiting ferroptosis through the activation of the Wnt/β-catenin signaling pathway, suggesting its potential as a treatment for androgenic alopecia.
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    Research cited in this study 15

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    6. Transcriptome Analysis Reveals an Inhibitory Effect of Dihydrotestosterone-Treated 2D- and 3D-Cultured Dermal Papilla Cells on Hair Follicle Growth Frontiers in Cell and Developmental Biology · 2021
    7. Physcion, a Novel Inhibitor of 5α-Reductase That Promotes Hair Growth In Vitro and In Vivo Archives of Dermatological Research · 2021
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    10. Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture Frontiers in Pharmacology · 2020
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