Suppression of Uterine and Placental Ferroptosis by N-Acetylcysteine in a Rat Model of Polycystic Ovary Syndrome

    November 2021 in “ Molecular Human Reproduction ”
    Min Hu, Yuehui Zhang, Shuting Ma … Håkan Billig
    Studysummary This study found that the antioxidant N-acetylcysteine attenuated ferroptosis in the uterus and placenta of a PCOS-like rat model, indicating its potential as a therapeutic strategy for PCOS-related complications.
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    Research cited in this study 3

    1. Hyperandrogenism and Insulin Resistance Modulate Gravid Uterine and Placental Ferroptosis in PCOS-Like Rats Journal of Endocrinology · 2020
    2. Comprehensive Overview of Polycystic Ovary Syndrome Nature Reviews Disease Primers · 2016
    3. Health Care-Related Economic Burden of Polycystic Ovary Syndrome During the Reproductive Life Span The Journal of Clinical Endocrinology and Metabolism · 2005