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Glossary mRNA expression

process of producing mRNA from a gene's DNA template

mRNA expression, also known as messenger RNA expression, refers to the process by which the information encoded in a gene is used to produce mRNA molecules. These mRNA molecules serve as templates for synthesizing proteins, which perform various functions in the body. Measuring mRNA expression levels can provide insights into how active a particular gene is under certain conditions, which is crucial for understanding biological processes and disease mechanisms, including those related to hair growth and alopecia.

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Research

5 / 1000+ results

research Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene

1 citations , February 2025 in “Journal of Dairy Science”

In this study, researchers found that the SLICK1 allele in cattle may alter local immune regulation, hair growth, and tissue remodeling, as indicated by differential gene expression pathways associated with immune and inflammatory responses in slick vs. nonslick Holsteins.

research Cyclosporin inhibits the apoptosis and effects the mRNA expressions of selected growth factors in cultured mouse hair follicles

January 2003 in “Journal of Clinical Dermatology”

This study found that cyclosporin A stimulated hair growth in mouse vibrissae follicles by promoting cell proliferation, reducing apoptosis, and altering the expression of certain growth factor mRNAs.

Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome

research Ovarian leukocyte distribution and cytokine/chemokine mRNA expression in follicular fluid cells in women with polycystic ovary syndrome

69 citations , September 2006 in “Human Reproduction”

This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.

research Effect of oleuropein on mRNA and protein expression of growth factors in C57BL/6N mouse skin tissue.

December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)”

This source provides procedural details without reporting new experimental findings or conclusions.

Antioxidant Enzyme Expression of mRNA and Protein in the Epididymis of Finasteride-Treated Male Rat Offspring During Postnatal Development

research Antioxidant enzyme expression of mRNA and protein in the epididymis of finasteride-treated male rat offspring during postnatal development

2 citations , September 2017 in “Archives of Medical Science”

The researchers reported that finasteride treatment in male rats may lead to changes in antioxidant enzyme activity in their offspring's epididymis, potentially affecting sperm maturation.

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Community Join

5 / 28 results

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 4 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 5 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community What an amazing time to be alive

in Finasteride/Dutasteride 187 upvotes 2 years ago

The post discusses a user's experience with hair loss treatments, specifically topical finasteride, minoxidil, and micro-needling, and their plan to switch to oral versions and add Dutasteride. The conversation includes various responses, with some users sharing their own experiences and side effects, and others expressing desire for a more permanent hair loss solution.

community Minoxidil is a 5ar inhibitor according to research

150 upvotes 11 months ago

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

community My understanding of how androgenetic alopecia works (plus FIN and DUT)

18 upvotes 4 years ago

Androgenetic alopecia is affected by scalp DHT levels, not sensitivity, with treatments like finasteride and dutasteride aiming to optimize these levels. Personalized DHT management is crucial for effective hair growth.

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Learn

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learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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