Physcion, a Novel Inhibitor of 5α-Reductase That Promotes Hair Growth In Vitro and In Vivo

February 2021 in “ Archives of Dermatological Research ”

Zizhao Lao, Yaohua Fan, Yuhang Huo, Feng Liao, Rongwen Zhang, Bei Zhang, Ziyun Kong, Haishan Long, Jieliang Xie, Chuanlan Sang, Lu‐Di Fu, Ji Lin, Yina Wu, Liangwen Yu, Geng Li

Physcion 5α-reductase dihydrotestosterone androgenic alopecia Polygonum multiflorum high-performance liquid chromatography hair follicle morphology molecular docking AGA DHT

Studysummary This study found that Physcion from Polygonum multiflorum may be an effective natural 5α-reductase inhibitor for treating androgenic alopecia by enhancing hair growth and improving follicle morphology in laboratory settings.

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