An Induced Pluripotent Stem Cell-Based Approach for Hair Follicle Development and Regeneration

    June 2024 in “ Regenerative Therapy ”
    Poornima Sivamani, Prakash Gangadaran, Prakash Gangadaran, Byeong‐Cheol Ahn
    Studysummary This review discussed the potential of induced pluripotent stem cells (iPSCs) for hair follicle regeneration, covering current approaches and challenges, iPSC differentiation, and their possible future clinical applications in hair restoration.
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    Research cited in this study 25

    1. Oral Drug As Effective As Topical Cream For Male Pattern Baldness JAMA · 2024
    2. Gene Therapy for Alopecia in Type II Rickets Model Rats Using Vitamin D Receptor-Expressing Adenovirus Vector Scientific Reports · 2023
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    18. Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice Scientific Reports · 2017
    19. Genetic Prediction of Male Pattern Baldness PLoS Genetics · 2017
    20. Induced Pluripotent Stem Cells From Human Hair Follicle Keratinocytes As A Potential Source For In Vitro Hair Follicle Cloning PeerJ · 2016
    21. The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial Stem Cells Translational Medicine · 2015
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    25. Follicular Unit Extraction Hair Transplant PubMed · 2010

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    1. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010