MicroRNA-Mediated Regulation of Hair Follicle Regeneration: Mechanisms, Delivery Strategies, and Translational Perspectives
June 2026
in “
Frontiers in Cell and Developmental Biology
”
micro-RNAs miRNAs hair follicle regeneration hair follicle stem cell activation immune microenvironmental homeostasis Wnt/β-catenin pathway Sonic hedgehog pathway TGF-β/BMP pathway alopecia areata lipid nanoparticles polymeric nanocarriers nucleic-acid strategies hair growth hair loss immune-mediated alopecia
Studysummary This review outlines recent advancements in understanding how micro-RNAs (miRNAs) influence hair regeneration, highlighting their role in stimulating hair growth and potential therapeutic approaches, while also addressing the challenges of clinical translation due to miRNAs' complex roles and delivery issues.
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