Androgenetic Alopecia in Transgender and Gender Diverse Populations: A Review of Therapeutics

    Julia Gao, Carl G. Streed, Julie D. Thompson, Erica D. Dommasch, Jon K. Peebles
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    TLDR The document concludes that treatments for hair loss in transgender and gender-diverse individuals include topical solutions, oral medications, laser therapy, and hair restoration procedures, with progress assessed after 6-12 months.
    The document reviews treatments for Androgenetic Alopecia (AGA) in transgender and gender-diverse patients. First-line treatments include topical minoxidil 5%, finasteride 1 mg, low-level laser light therapy, and for transfeminine patients, spironolactone 200 mg. Second-line options include oral minoxidil (1.25 mg for transfeminine and 2.5 mg for transmasculine patients), topical finasteride 0.25% alone or with minoxidil 2%, oral dutasteride 0.5 mg, platelet-rich plasma, or hair restoration procedures. Treatment progress should be assessed after 6-12 months using non-sex-based scales like the Basic and Specific Classification or the Bouhanna scales. Dermatologists should coordinate with the patient's primary gender-affirming clinician(s) to ensure shared knowledge of all medications.
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      in Chat  36 upvotes 1 month ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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