Androgenetic Alopecia in Transgender and Gender Diverse Populations: A Review of Therapeutics

    October 2021 in “ Journal of The American Academy of Dermatology ”
    Julia Gao, Carl G. Streed, Julie D. Thompson … Jon K. Peebles
    Studysummary This review discusses treatment options for androgenetic alopecia in transgender and gender-diverse patients, highlighting first-line treatments like topical minoxidil and finasteride, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 48

    1. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    2. Incidence and Factors Associated With Androgenetic Alopecia Among Transgender and Gender-Diverse Patients Treated With Masculinizing Hormone Therapy JAMA Dermatology · 2021
    3. Intradermal Injections With 0.5% Minoxidil for the Treatment of Female Androgenetic Alopecia: A Randomized, Placebo-Controlled Trial Dermatologic Therapy · 2020
    4. Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride JAMA Dermatology · 2020
    5. Ongoing Concerns Regarding Finasteride for the Treatment of Male-Pattern Androgenetic Alopecia JAMA Dermatology · 2020
    6. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    7. Characterization and Management of Hypertrichosis Induced by Low-Dose Oral Minoxidil in the Treatment of Hair Loss Journal of The American Academy of Dermatology · 2020
    8. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    9. A Systematic Review of the Effect of Platelet-Rich Plasma on Androgenetic Alopecia in Women Dermatologic Therapy · 2020
    10. Treatment of Male and Female Pattern Hair Loss with Sublingual Minoxidil: A Retrospective Case-Series of 64 Patients Journal of The European Academy of Dermatology and Venereology · 2020
    11. Spironolactone for Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2020
    12. Androgenetic Alopecia: Effects of Oral Finasteride on Hormone Profile, Reproduction, and Sexual Function Endocrine · 2020
    13. Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: A Review of the Literature Skin appendage disorders · 2020
    14. Androgenetic Alopecia in Gender Minority Patients Dermatologic Clinics · 2019
    15. Very-Low-Dose Oral Minoxidil in Male Androgenetic Alopecia: A Study with Quantitative Trichoscopic Documentation Journal of The American Academy of Dermatology · 2019
    16. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    17. Efficacy of Platelet-Rich Plasma for Treating Androgenic Alopecia of Varying Grades Clinical Drug Investigation · 2019
    18. Hair Loss Among Transgender and Gender-Nonbinary Patients: A Cross-Sectional Study British Journal of Dermatology · 2019
    19. Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenetic Alopecia Journal of The American Academy of Dermatology · 2019
    20. The Efficacy and Safety of Dutasteride Compared with Finasteride in Treating Men with Androgenetic Alopecia: A Systematic Review and Meta-Analysis Clinical Interventions in Aging · 2019
    21. Shedding Light on the FDA’s 510(k) Approvals Process: Low-Level Laser Therapy Devices Used in the Treatment of Androgenetic Alopecia Journal of Dermatological Treatment · 2018
    22. Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol International Journal of Women's Dermatology · 2018
    23. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    24. Understanding and Addressing Hair Disorders in Transgender Individuals American Journal of Clinical Dermatology · 2018
    25. Female Pattern Hair Loss: A Pilot Study Investigating Combination Therapy with Low-Dose Oral Minoxidil and Spironolactone International Journal of Dermatology · 2017
    26. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
    27. Therapeutic Experience with Oral Finasteride for Androgenetic Alopecia in Female-to-Male Transgender Patients Clinical and Experimental Dermatology · 2017
    28. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
    29. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    30. Quality of Life Assessment in Patients with Alopecia Areata and Androgenetic Alopecia in the People's Republic of China Patient Preference and Adherence · 2017
    31. A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia International Journal of Trichology · 2017
    32. Dermatologic Care of the Transgender Patient International Journal of Women's Dermatology · 2016
    33. Hormonal and Surgical Treatment Options for Transgender Men (Female-to-Male) Psychiatric Clinics of North America · 2016
    34. Meta-Analysis of Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia Journal of Dermatological Treatment · 2016
    35. Cross-Sex Hormone Therapy in Trans Persons Is Safe and Effective at Short-Term Follow-Up: Results from the European Network for the Investigation of Gender Incongruence The Journal of Sexual Medicine · 2014
    36. Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study American Journal of Clinical Dermatology · 2014
    37. Short- and Long-Term Clinical Skin Effects of Testosterone Treatment in Trans Men The Journal of Sexual Medicine · 2013
    38. Hairline Lowering: A Cosmetic Procedure for Women with High Hairlines Facial Plastic Surgery Clinics of North America · 2013
    39. Patient Selection, Candidacy, and Treatment Planning for Hair Restoration Surgery Facial Plastic Surgery Clinics of North America · 2013
    40. Androgens and Hair Growth Dermatologic Therapy · 2008
    41. A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification Journal of The American Academy of Dermatology · 2007
    42. The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride Journal of The American Academy of Dermatology · 2006
    43. Effects of Finasteride (1 mg) on Hair Transplant Dermatologic Surgery · 2005
    44. Treatment of Female Pattern Hair Loss With Oral Antiandrogens British Journal of Dermatology · 2005
    45. Hypertrichosis in Females Applying Minoxidil Topical Solution and in Normal Controls Journal of The European Academy of Dermatology and Venereology · 2003
    46. Multifactorial Classification of Male and Female Androgenetic Alopecia Dermatologic Surgery · 2000
    47. Psychological Effects of Androgenetic Alopecia on Women: Comparisons with Balding Men and Female Control Subjects Journal of The American Academy of Dermatology · 1993
    48. The Psychological Effects of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 1992

    Related research 10

    1. What's New in Therapy for Male Androgenetic Alopecia? American Journal of Clinical Dermatology · 2022
    2. Comparison of Oral Minoxidil, Finasteride, and Dutasteride for Treating Androgenetic Alopecia Journal of Dermatological Treatment · 2022
    3. Androgenetic Alopecia in Transgender and Gender Diverse Populations: A Review of Therapeutics Journal of The American Academy of Dermatology · 2021
    4. LB792 Minoxidil and Dutasteride Drug Tattooing for Male Androgenetic Alopecia Journal of Investigative Dermatology · 2021
    5. Mesotherapy with Dutasteride and Minoxidil in the Treatment of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2018
    6. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    7. Retrospective Evaluation of the Application of Dutasteride, Unapproved by the FDA, for Male Pattern Baldness in Korea 한국임상약학회지 · 2015
    8. Luncheon Symposium: Update on the Efficacy and Safety of Dutasteride in the Management of Androgenetic Alopecia 프로그램북(구 초록집) · 2015
    9. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2004
    10. Improvement in Androgenetic Alopecia (Stage V) Using Topical Minoxidil in a Retinoid Vehicle and Oral Finasteride Archives of Dermatology · 1995